
Mast cell activation is gaining attention among patients and practitioners, yet this phenomenon is far from new. Mast Cell Activation Syndrome (MCAS) is a chronic condition involving excessive or dysregulated release of mast cell mediators—histamine, tryptase, prostaglandins, leukotrienes, and many others—affecting multiple systems in the body. Symptoms such as flushing, itching, brain fog, fatigue,… Read more »