MAST CELL & ALLERGY SUPPORT
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HistaQuel® is a comprehensive formula providing a multi-faceted, systemic approach to supporting healthy mast cell function and histamine response.*
Mast cells are part of the immune system and are primarily responsible for generating and releasing histamine in the body. Under typical conditions, this is a natural function of a healthy body working to rid itself of an allergen. However, mast cells can become overactive, releasing a cascade of histamine throughout the body, which results in heightened or continuous allergy symptoms.
Many allergy support supplements, such as diamine oxidase (DAO), focus on reducing histamine within the gut by utilizing enzymes to degrade the histamine. Unfortunately, this means they are limited in their function and only effective for reducing ingested histamine (i.e., histamine introduced to the body through the food we eat) within the GI tract. However, mast cells release histamine systemically. Therefore, when mast cells are activated, they release histamine throughout the body. Enzymes such as DAO do nothing to address the healthy function of mast cells or support the body's healthy response to histamine and therefore serve limited benefit.
HistaQuel® utilizes a comprehensive approach to support healthy mast cell function and histamine response systemically.* Six clinically researched flavonoids and herbs have been combined to promote healthy levels of histamine production and healthy levels of histamine absorption. This holistic approach resulted in a comprehensive formula featuring dual mechanisms of action.*
| Features | Constituents/Actions | Benefits* |
| Mast Cell Secure™ | Fisetin, Luteolin, Perilla frutescens, Quercefit® Quercetin Phytosome® | • Targeted flavonoid blend supports a healthy mast cell release of histamine • Moderates interactions between mast cells and activated T cells • Supports a healthy Th2 release of allergy promoting cytokines IL-4 and IL-5 • Supports a healthy IgE mediated release of histamine • Highly bioavailable form of Quercetin with 20 times increased absorption compared to standard Quercetin in published research |
| HistaCheck™ | Stinging Nettle Leaf, Black Cumin (seed) extract | • Promotes a healthy level of histamine to bind to its receptors by competitive inhibition • Supports management of a healthy immune system response to allergens |
Notice: Due to VAT laws in the UK and our agreement with our European distributor, we are not able to ship orders to the UK. Please contact www.nutrined.com to complete your purchase.
Read the ResearchPurchase BioDisrupt®
BioDisrupt® supports the healthy immune system’s ability to target the sophisticated self-defense mechanisms of biofilms.* BioDisrupt® is a clinically researched formula featuring two proprietary blends: EnzymeDisrupt™ and HerbDisrupt™. These blends work synergistically to provide comprehensive microbial biofilm support by disrupting the biofilm matrix and inhibiting the formation of new biofilms.*Read the researchPurchase ATP 360®
ATP360® is a comprehensive mitochondrial support formula utilizing powerful ingredients to provide targeted support.
Clinical human research has been peer-reviewed and published in Alternative Therapies May/Jun 2021 Vol. 27 No. 3
This human study demonstrated significant improvements in energy in as little as 2 weeks.* Additional study results showed ATP360’s® ability to support sleep and healthy cardiovascular function.*[2]
Read the researchPurchase Tri-Fortify®
Tri-Fortify® is a delicious tasting, heat stable (no refrigeration required) oral liposomal glutathione supplement with clinically proven absorption.
Penn State University conducted a 2-week human study using Tri-Fortify® to assess changes in intracellular glutathione absorption (not just plasma levels). Researchers also looked at natural killer cell function and oxidative stress markers.
The study showed a 28% increases in intracellular glutathione levels after just 2 weeks of use, as well as demonstrating its ability to support healthy NK cell function and oxidative stress levels.*¹
[1] Sinha R, Sinha I, Calcagnotto A, et al. Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function. Eur J Clin Nutr. 2018;72(1):105-111. doi:10.1038/ejcn.2017.132
Read the researchLearn More About Transfer Factor Multi-Immune™
Transfer Factor Multi-Immune™ is an advanced immune support formula comprising a proprietary blend of bovine derived transfer factors and whole colostrum, along with multiple immune supporting herbs, and mushrooms.
Multiple clinical studies on Transfer Factor Multi-immune™ have demonstrated substantial increases in Natural Killer cell function, as well as the ability to support immune modulation.*
¹Jensen GS, Cruickshank D, Hamilton DE. Effects of a β-Glucan-Rich Blend of Medicinal Mushrooms and Botanicals on Innate Immune Cell Activation and Function Are Enhanced by a Very Low Dose of Bovine Colostrum Peptides. Molecules. 2024 Jun 12;29(12):2787. doi: 10.3390/molecules29122787.
Read the researchPurchase CytoQuel®
CytoQuel®, backed by peer-reviewed research published in the Journal of Pain Research, is a comprehensive blend to promote healthy cytokine function.*
In an 8-week human clinical study, CytoQuel® showed statistically significant evidence of its ability to support healthy cytokine function. The Study indicated CytoQuel’s® ability to promote healthy cardiovascular function, support improved quality of sleep, and promote normal MMP-9 levels. [3]
[3] Hamilton DE, Jensen GS. Pain reduction and improved vascular health associated with daily consumption of an anti-inflammatory dietary supplement blend. J Pain Res. 2019 May 15;12:1497-1508. doi: 10.2147/JPR.S189064. PMID: 31190960; PMCID: PMC65267
Read the ResearchLearn More About BDNF Essentials®
BDNF Essentials® is a comprehensive formula designed to support neurological health and cognitive function. This unique formula leverages ingredients that have been shown to aid in the formation of nerve growth factors such as BDNF (Brain-derived neurotrophic factor). BDNF is essential in supporting neuron health, neuroplasticity, and neurogenesis.
Clinical research demonstrated that BDNF Essentials® significantly improved reaction time in measures of working memory, episodic memory (long-term memory of specific events or episodes), and attention, as well as in mood.*
Research also indicated reduced salivary cortisol and IL-6. These data suggest the use of BDNF Essentials® to support the age-related decline in cognitive function and memory.*
[1] Lewis D. Erin, Crowley C. David, Hamilton Debby, Guthrie Najla and Evans Malkanthi*, An Open-label Exploratory Study Investigating BDNF Essentials® on Cognition in Healthy Adults with Self-reported Memory Complaints, Current Nutraceuticals 2023; 4 : e171123223619 . https://dx.doi.org/10.2174/0126659786256669230930114915
