Vagal Nerve Vitality Bundle

Vagal Nerve Vitality Bundle

The Vagal Nerve Vitality Bundle combines BDNF Essentials®, ATP 360®, and RenewGut Thrive™ to support the interconnected biology behind healthy vagus nerve function, stress resilience, and recovery.* By supporting neuronal communication, mitochondrial response capacity, and gut-derived signaling, this coordinated system helps the body communicate, respond, and return to baseline after ongoing stress.* When the body lacks the nutritional support needed to respond, it may be harder to shift out of fight-or-flight, even with practices such as breathing, meditation, movement, and healthy sleep.*

The vagus nerve is a major communication pathway linking the brain, gut, immune system, and mitochondria. Repeated physical, emotional, immune, metabolic, or environmental stress can increase allostatic load, the body’s accumulated strain from ongoing stress, and make it harder to shift out of a sympathetic-dominant, fight-or-flight state. This may be experienced as reduced stress tolerance, persistent fatigue or brain fog, disrupted or nonrestorative sleep, or occasional digestive discomfort. BDNF Essentials® supports healthy neuronal membranes, cognitive resilience, and nutrient-dependent cholinergic pathways. ATP 360® supports mitochondrial membrane integrity, cellular energy production, redox balance, and the capacity to respond to vagal signals. RenewGut Thrive™ supports intestinal barrier and mucosal integrity, microbial balance, postbiotic signaling, and healthy immune communication within the GI tract.*

SAVE 10% on your first order.

Discount is applied when you add the bundle to your cart. Exp 9/30/26

Three Formulas. One Connected System.
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    Supports stress resilience*

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    Supports cognitive resilience*

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    Supports cellular energy*

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    Supports gut-brain signaling*

  • ATP 360®

  • BDNF Essentials®

  • RenewGut Thrive™

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Product information

Supplement Facts / Dosing

ATP 360®

Vitamin C (from Membrane Restore™ Blend) | 100 mg

Thiamin (from Krebs Plus Foundation™ Blend) | 50 mg
Riboflavin (as Riboflain-5-phosphate) (from Membrane Potential™ Blend) | 65 mg

Choline (from RN Lipid Concentrate™ Blend) | 27 mg

Magnesium (from Krebs Plus Foundation™ Blend) | 50 mg

Membrane Potential™ | 215 mg
CoQ10, Riboflavin-5-Phosphate, Panmol® (NADH)

Membrane Restore™ | 186 mg
Ascorbic Acid, DeltaGold® Tocotrienols (derived from Annatto)

RN Lipid Concentrate™ | 400 mg
Phospholipids incl. Phosphatidylcholine, Phosphatidylethahanolamine, Phosphatidylinositol)

Krebs Plus Foundation™ | 225 mg
R-Lipoic Acid, Alpha Ketoglutaric Acid, Magnesium (as Di-Magnesium Malate), Thiamine HCl

Mitogenesis RN™ | 210 mg
Acetyl L-Carnitine, PQQ (Pyrroloquinoline Quinone)

Other Ingredients: Hypromellose (vegetable capsule), rice hull extract, calcium carbonate, and mineral silica.

Contains: Ingredients derived from soy.

Manufactured without milk, eggs, fish, crustacean shellfish, sesame, tree nuts, peanuts, wheat and gluten. Produced in a facility that may process other ingredients containing these allergens.

Vegetarian

GMO-free

Suggested Use: Take 3 capsules once daily with or without food.

Cautions: If pregnant or nursing, consult your health care professional before use.

BDNF Essentials®

Choline (as Cytidine Diphosphate Choline Sodium Salt)*** 25 mg

Sodium (as Cytidine Diphosphate Choline Sodium Salt)*** 5 mg

NeuroCyto Protect™ Blend | 1175 mg
Organic Lion’s Mane Mushroom (Hericium erinaceus) mycelium and fruiting body powder, Skullcap (Scutellaria lateriflora) Herb Powder, Black Rice (Oryza sativa) Seed Extract (25% Anthocyanins), Bacopa (Bacopa monnieri) Herb Powder, Sensoril® Ashwagandha (Withania somnifera) Root and Leaf Extract.

Cognition Blend | 175 mg
CDP Choline Sodium Salt, Sharp-PS® Green Phosphatidylserine

Vegetarian

GMO-free

Soy Free

Suggested Use: As a dietary supplement, take 2 capsules twice daily with or without meals, or as directed by your health care professional.

Cautions: If pregnant or nursing, consult your health care professional before use.

***Sodium and Choline are from Cognition Blend

Sensoril® is a registered trademark of Natreon, Inc.

Sharp-PS® is a registered trademark of Enzymotec USA, Inc.

RenewGut Thrive™

Tight Junction Enhancer | 1725 mg
Hydrolyzed collagen peptides (type I & III), N-Acetyl D-glucosamine, GutGard® deglycyrrhized licorice, Zinc Carnosine

Mast Cell Manager | 175 mg
Black Cumin (Nigella sativa) (seed), Luteolin

ImmunoMetabolic Booster | 350 mg
Tributyrin (as CoreBiome®), Akkermansia (as pasteurized Akkermansia muciniphila)
Other Ingredients:Gelatin (capsule), magnesium stearate and natural flavors.

Manufactured without milk, eggs, fish, tree nuts, peanuts, shellfish, sesame, wheat, soy, and gluten. Produced in a facility that may process other ingredients containing these allergens.

GMO-free

Suggested Use: As a dietary supplement, take 5 capsules first thing in the morning with food or as directed by your healthcare professional.

Caution: Not for use by women who are pregnant or may become pregnant.

Communicate, Respond & Recover

  • BDNF Essentials®

    COMMUNICATION CAPACITY

    Supports healthy neuronal membranes, cognitive resilience, and nutrient-dependent pathways involved in acetylcholine and cholinergic communication.*

  • ATP 360®

    MITOCHONDRIAL RESPONSE & RECOVERY CAPACITY

    Supports mitochondrial membrane integrity, cellular energy production, antioxidant defenses, and the cellular capacity needed to respond to vagal and cholinergic signals during periods of increased physiological demand.*

  • RenewGut Thrive™

    GUT DERIVED SIGNALING AND INTEGRATION

    Supports intestinal barrier and mucosal integrity, microbial balance, postbiotic signaling, and healthy mast-cell and immune communication in the GI tract. This helps maintain gut-derived communication within the broader vagal-immune-metabolic network.*

  • Three Targets. One Strategy.

    Together, the three formulas support signal, response, and integration across an interconnected vagal-immune-mitochondrial-gut network, helping reinforce the body’s capacity to communicate, respond, and recover.*

Mechanisms of Action

Supports vagal and neuronal communication*

Supports mitochondrial response capacity*

Supports gut-derived signaling and barrier integrity*

Promotes healthy immune and redox balance*

Supports stress regulation and recovery capacity*

From Signal to Recovery

Healthy vagus nerve function depends on more than stimulating a signal. The vagus nerve uses acetylcholine-related communication to help coordinate parasympathetic regulation, gut-brain signaling, immune activity, and the transition toward recovery. When immune signaling and oxidative stress remain elevated, mitochondrial demand rises and may limit the body’s ability to respond. Supporting neuronal membranes and cholinergic pathways, mitochondrial energy and redox balance, and gut-derived signals helps reinforce communication across the broader vagal-immune-mitochondrial-gut network. The goal is to support an appropriate transition from defense to resolution, repair, and recovery.*

Why Support the Vagus Nerve?

The vagus nerve is one of the body’s primary communication routes between the brain and organs, especially the digestive tract. Repeated physical, emotional, immune, metabolic, or environmental stress can bias the body toward a sympathetic-dominant, fight-or-flight state and make it harder to return to baseline. Targeted nutrition helps support the cellular membranes, energy production, and gut environment required for the body to receive and respond to those signals.*

Common Signs You May Need More Support

  • Reduced stress tolerance or slow recovery
  • Persistent fatigue, brain fog, or reduced stamina
  • Disrupted or nonrestorative sleep
  • Occasional GI discomfort or irregularity

“Within the Gut-Brain-Immune Optimization pillar of my V.A.G.U.S. Protocol, I look for scientifically proven tools that support the ongoing conversation between the gut, the brain, and the immune system. ATP 360®, BDNF Essentials®, and RenewGut Thrive™ do exactly that by addressing mitochondrial resilience, neuroplasticity, and gut barrier integrity in a coordinated way. This combination is my preferred combination for patients working to restore healthy Vagus nerve signaling, through a genuinely comprehensive and well researched foundation.”

- Dr. Navaz Habib, DC, AFMCP, Acu P
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Frequently Asked Questions

What does the vagus nerve do?

The vagus nerve is a major communication pathway between the brain and organs, especially the digestive tract. It helps coordinate parasympathetic activity (or rest-and-digest), gut-brain communication, immune signaling, and the transition from a stress response toward recovery.

How does the bundle support healthy vagus nerve function?

BDNF Essentials® supports healthy neuronal membranes and nutrient-dependent cholinergic pathways. ATP 360® supports mitochondrial membrane integrity, cellular energy, and redox balance. RenewGut Thrive™ supports barrier integrity, microbial and postbiotic signaling, and healthy immune communication in the GI tract. Together, they support the biology needed to communicate, respond, and recover.*

Who may benefit from vagus nerve support?

This bundle may be appropriate for adults seeking nutritional support for reduced stress tolerance, slow recovery after ongoing stress, persistent fatigue or brain fog, disrupted or nonrestorative sleep, difficulty winding down, or occasional digestive discomfort or irregularity. Consult your healthcare practitioner for personalized guidance.

Why is mitochondrial support included in a vagus nerve bundle?

Vagal signals have limited value if neurons and target cells lack the energy and resilience to respond. Mitochondria produce ATP and participate in membrane integrity, redox balance, stress-response signaling, and immune communication. ATP 360® helps support this mitochondrial response capacity.*

How does gut health influence vagus nerve communication?

The intestinal environment continually sends information to the nervous and immune systems. Barrier integrity, the mucin layer, microbial metabolites, and immune activity influence the quality of gut-derived signals. RenewGut Thrive™ supports these pathways to help maintain communication across the broader vagal-immune-metabolic network.*

Does the bundle directly stimulate the vagus nerve?

No. Lifestyle practices such as slow breathing, meditation, movement, and sleep can help stimulate vagal signaling, but the body also needs adequate nutritional support to receive and respond to those signals. The bundle provides targeted support for the neuronal, mitochondrial, and gut biology involved in that response.*

How should I take the products in the bundle?

Take each formula according to its product label or as directed by your healthcare practitioner.

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